Dr. Lisa Derosa has presented ONCOBIOME last results.
Four lines of evidence point to the biological significance of the composition of the gut microbiota in influencing peripheral immune tonus and effectiveness of ICI in patients with cancer:
- the impact of antibiotics on cancer immunotherapy;
- metagenomics based fingerprints dictating long term survival or primary resistance to immunotherapy;
- avatar mice demonstrating cause effect relationship
- pilot studies using fecal microbial transplantation